Table 3.

Strength and direction of recommendations

Judgment	Recommendations
The desirable effects clearly outweigh the undesirable effects	Strong for an intervention
The desirable effects are likely to outweigh the undesirable effects	Weak for an intervention
The balance between undesirable and desirable effects is closely balanced or uncertain	Recommendation for research and for limited use within clinical trials
The undesirable are likely to outweigh the desirable effects	Weak against an intervention
The undesirable clearly outweigh the desirable effects	Strong against an intervention
Best practice recommended based on the clinical experience of the expert panel	Good Practice Point (GPP)