Table 1.

Different values for the three parameter sets Default, Paper, and Thesis

Parameter	Unit	Default	Paper	Thesis	Description
Initial Values
${\left[C{a}^{2+}\right]}_e$	mM	0.01963	0.025	0.019	$C{a}^{2+}$ in ER
${\left[N{a}^{+}\right]}_{\mathrm{t}\mathrm{o}\mathrm{t}}$	mM	165	160	160	Tot. $N{a}^{+}$ available
${\left[N{a}^{+}\right]}_{\text{out}}$	mM	150	145	145	$N{a}^{+}$ in extracelluar space
$V_m$	V	−0.08588	−0.085	−0.085	Membrane voltage
Parameters
$I_{\mathrm{G}\mathrm{l}\mathrm{u}{\mathrm{T}}_{max}}$	$\frac{pA}{\mu m^2}$	0.75	0.68	0.75	Max. current of $I_{\mathrm{G}\mathrm{l}\mathrm{u}\mathrm{T}}$
$I_{\mathrm{N}\mathrm{C}{\mathrm{X}}_{max}}$	$\frac{pA}{\mu m^2}$	0.001	0.1	0.1	Max. current of $I_{\mathrm{N}\mathrm{C}\mathrm{X}}$
$g_{\mathrm{N}{\mathrm{a}}_{\text{Leak}}}$	$\frac{\mu S}{\mu m^2}$	13	6.5	13	Conductance of ${\text{NA}}^{+}$ leak
$g_{{\mathrm{K}}_{\mathrm{L}\mathrm{e}\mathrm{a}\mathrm{k}}}$	$\frac{\mu S}{\mu m^2}$	162.46	79.1	162.46	Conductance of ${\mathrm{K}}^{+}$ leak
${\nu }_{\beta }$	$\frac{mM}{s}$	1e-4	5e-5	5e-5	Max. production of $I{P}_3$ by PLC $\beta$
$r_L$	$\frac{1}{s}$	0.055	0.11	0.11	$C{a}^{2+}$ leak rate between ER and intracellular space
$r_C$	$\frac{1}{s}$	3	6	6	Max. CICR rate
${\nu }_{ER}$	$\frac{mM}{s}$	0.0045	0.004	0.004	Max. $C{a}^{2+}$ uptake by SERCA