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[Preprint]. 2023 May 24:2023.05.23.541898. [Version 1] doi: 10.1101/2023.05.23.541898

Fig. 5|. Depletion of PfAP2-MRP increases chromatin accessibility.

Fig. 5|

a, Chromatin contact count heatmap of chromosome 7 at 16 h.p.i. (top) and 40 h.p.i (bottom) for the WT (left) and Δpfap2-mrp (middle), as well as the log! fold change in interactions (right) between the WT and Δpfap2-mrp. Blue indicates a loss of interactions and red indicates an increase of interactions Δpfap2-mrp over WT. b, Whole-genome interchromosomal contact count heatmaps at 16 h.p.i. for the WT (left) and Δpfap2-mrp (right). Chromosomes are sorted from left to right and bottom to top. Intrachromosomal interactions are removed. c, Whole-genome 3D chromatin models at 16 h.p.i. for the WT (left) and Δpfap2-mrp (right). Centromeres (blue), telomeres (green), and var genes (red) are enhanced to display differences between the two samples. d, Number of interactions between var gene containing bins.