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Lead SNP rs2058019 demonstrates association with severe ROP disease in Hispanic and Caucasian populations but not in African American populations
| Effect Allele | AF: Case | AF: Control | AF: All | OR | P |
|---|---|---|---|---|---|
| T | 0.22 | 0.08 | 0.11 | 1.26 | 2.95E-06 |
| T | 0.04 | 0.01 | 0.01 | 1.61 | 4.0E-04 |
| T | 0 | 0.02 | 0.01 | 0.87 | 0.49 |
| T | 0.14 | 0.04 | 0.06 | 1.27 | 4.96E-9 |
HA: Hispanic Americans; CA: Caucasian Americans; AA: African Americans; All: all subjects combined.
AF: allele frequency of effect allele.
