Table 8.

Association of SNPs identified with severe ROP.

SNP	MaF	gene	P for severe ROP (Hamett, 2014)	P for ROP ≥ Stage 3 (iROP)
rs9332681	Na	F5	0.99	Na
rs379489	0.287	CFH	3.8E-03	0.I4
rs395544	0.287	CFH	5.4E-03	0.14
rs11587174	0.002	FI3B	0.87	na
rs1467199	0.211	STATI	0.82	0.81
rs34417936	0.014	IL	0.66	Na
rs2299386	0.380	RELN	1.6E-03	0.73
rs10251365	0.332	RELN	1.0E-03	0.0092*
rs168879811	0.309	NRGI	4.0E-04	0.28
rs168879814	0.311	NRGI	3.0E-04	0.25
rs2353512	0.002	BDNF-AS	0.77	Na
rs7127507	0.295	BDNF	2.0E-04	0.70
rs2049046	0.479	BDNF	3.00E-05	0.41
rs7934165	0.471	BDNF	2.00E-05	0.53
rs12281784	0.101	LRP4	0.54	0.14
rs9989002	0.211	IGFI	2.2E-03	0.81
rs11620315	0.149	FLTI	0.45	0.76
rs1319859	0.424	IGFIR	0.12	0.04
rs884636	0.040	PCPEPIL	0.10	na
rs7204874	Na	NSMC EIjIL4 R	1.4E-03	na
rs2057768	0.287	IL4R	7.0E-04	0.65
rs1551005	Na	TTR	0.96	na

MAF: minor allele frequency.

na: SNP not available in ROP dataset and/or with MAF less than 0.05.