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[Preprint]. 2023 May 26:2023.05.19.23290192. [Version 1] doi: 10.1101/2023.05.19.23290192

Figure 2. Longitudinal human milk IgA and sAb against SARS-CoV-2 Nucleocapsid are maintained less consistently compared to Spike Abs and subject to significant background reactivity.

Figure 2.

(A-C) Titration curves of IgA and sAb 3-8 weeks post-infection. A) IgA; B) sAb, C) high background IgA of COVID-19-naïve milk hinders determination of a positive cutoff value. MFI at 1/18 dilution (screening dilution) are shown. (D-E) Individual endpoint titers over time. D) IgA, E) sAb. (F-G) Grouped endpoint titers with mean values and ANOVA analysis for change over time. F) IgA, G) sAb. Relative endpoint titers over time compared to 3-8 weeks post-infection. H) IgA, I) sAb. Dotted line indicates relative titer of 1, meaning no change. PI: post-infection.