Table II.
Group 1 (Cocaine) |
Group 2 (Other drugs) |
Group 3 (No drugs) |
P | |
---|---|---|---|---|
| ||||
Sample size (n) | ||||
Birth | 95 | 110 | 97 | |
2–6 months | 71 | 89 | 77 | |
HR | ||||
Birth | 132.75(0.93) | 130.27 (0.85) | 130.67 (0.92) | .127 |
2–6 months | 142.74(1.08)¶ | 141.88 (0.95)¶ | 143.70(1.04)¶ | .431 |
RMSSD | ||||
Birth | 20.33 (0.63) | 22.04 (0.65) | 21.19 (0.59) | .088 |
2–6 months | 21.97 (0.80)¶ | 20.39 (0.45) | 19.65 (0.56) | .022§ |
SDNN | ||||
Birth | 41.88(1.15) | 47.64(1.15) | 46.82(1.23) | .002†‡ |
2–6 months | 49.94(1.14)¶ | 49.07 (1.00) | 47.82(1.04) | .297 |
HF | ||||
Birth | 50.32 (3.89) | 69.36 (5.54) | 59.04 (4.37) | .006‡ |
2–6 months | 75.54 (7.49)¶ | 62.15 (4.49) | 60.63 (5.07) | .089 |
LF | ||||
Birth | 122.99 (8.89) | 161.23 (10.69) | 138.61 (8.13) | .012‡ |
2–6 months | 150.34(11.94)¶ | 145.34 (9.74) | 134.09 (7.97) | .271 |
Total | ||||
Birth | 872.97 (59.76) | 1196.00 (83.01) | 1125.44 (79.70) | .234 |
2–6 months | 1224.38 (93.91)¶ | 1215.15(127.79) | 1097.37(92.84) | .021 § |
VLF | ||||
Birth | 251.40 (26.15) | 303.65 (23.55) | 271.36 (21.07) | .858 |
2–6 months | 208.98 (20.61) | 276.45 (60.54) | 211.15 (32.30)¶ | .263 |
ULF | ||||
Birth | 472.46(32.81) | 661.47 (57.85) | 656.79 (59.75) | .176 |
2–6 months | 792.69 (65.08)¶ | 732.27 (65.24) | 691.77 (59.87) | .013§|| |
SNN-50 | ||||
Birth | 4320.09 (404.41) | 5743.43 (468.23) | 4835.27 (425.12) | .047‡ |
2–6 months | 6565.65 (709.79)¶ | 4905.06 (406.52) | 4752.39 (519.28) | .025§ |
SDNNI | ||||
Birth | 27.78 (0.90) | 31.33 (0.91) | 30.46 (0.95) | .035‡ |
2–6 months | 29.61 (0.86) | 29.18(0.71) | 28.23 (0.66) | .288 |
SDANN | ||||
Birth | 31.89(1.29) | 35.62(1.29) | 35.16 (1.01) | .078 |
2–6 months | 39.18(1.53)¶ | 38.77 (1.22) | 36.99 (0.98) | .097 |
Values are presented as mean (SE), unless otherwise indicated.
P values are calculated from the repeated measures analyses adjusting for body surface area.
Cocaine versus no drugs at birth.
Cocaine versus other drugs at birth.
Cocaine versus no drugs at 2 to 6 months.
Cocaine versus other drugs at 2 to 6 months.
Significant change at 2 to 6 months of age from birth (P < .015).