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. 2023 Jun 7;131(6):067001. doi: 10.1289/EHP11545

Figure 4.

Figure 4 is an error bar graph, plotting risk ratio of overweight to obesity, ranging from 0.5 to 2.5 in increments of 0.25 (y-axis) across analyte quintiles, including perfluorooctanoic acid, perfluorooctanesulfonic acid, perfluorononanoic acid, perfluorohexane sulfonic acid, perfluorodecanoic acid, perfluroundecanoic acid, N-methyl perfluorooctane sulfonamido acetic acid (x-axis) for quintile 1, quintile 2, quintile 3, quintile 4, and quintile 5.

Adjusted relative risk of child overweight/obesity across quintiles of PFAS concentrations during pregnancy: the ECHO Cohorts. Models were adjusted for sex of the child (2 categories), child age, maternal race (3 categories), maternal Hispanic ethnicity (2 categories), maternal age at delivery, highest level of maternal education at pregnancy (4 categories), and maternal prepregnancy BMI. Models included random intercepts for participant and cohort. Cutoffs for quintiles and the full corresponding numerical results in this figure are presented in Table S12. Shapes show the reference, and point estimates for the risk ratio of overweight/obesity for each quintile of log2-transformed PFAS analyte. Error bars represent the lower and upper confidence intervals for each point estimate. Quintile 1 is the reference group for each analyte. Note: BMI, body mass index; NMFOSAA, N-methyl perfluorooctane sulfonamido acetic acid; PFAS, per- and polyfluoroalkyl substances; PFDA, perfluorodecanoic acid; PFHxS, perfluorohexane sulfonic acid; PFNA, perfluorononanoic acid; PFOA, perfluorooctanoic acid; PFOS, perfluorooctanesulfonic acid; PFUnDA, perfluroundecanoic acid; Q, quintile.