Preparation of various organic compounds by Suzuki coupling reaction under optimum conditionsa.
Entry | Aryl boronic acid | Aryl halide | Product | Time (min) | Yield (%) |
---|---|---|---|---|---|
1 | 60 | 92 | |||
2 | 60 | 95 | |||
3 | 60 | 97 | |||
4 | 60 | 99 | |||
5 | 60 | 77 | |||
6 | 92 | 92 | |||
7 | 60 | 95 | |||
8 | 60 | 99 | |||
9 | 60 | 98 | |||
10 | 60 | 99 | |||
11 | 60 | 98 | |||
12 | 73 | 99 | |||
13 | 60 | 76 | |||
14 | 60 | 95 | |||
15 | 60 | 90 | |||
16 | 60 | 98 | |||
17 | 60 | 96 | |||
18 | 90 | 99 | |||
19 | 60 | 97 | |||
20 | 60 | 95 | |||
21 | 93 | 35 |
Conditions for the chemical reaction: 1 mmol of aryl halide, 1 mmol of aryl boronic acid, 70 °C, EtOH 78%, K2CO3.