Fig 3. Persistence of anti-filarial antibodies after treatment in a Papua New Guinea treatment trial.

Graphs show the persistence, as a percentage of the ELISA OD₄₉₀ values for antibodies to the indicated recombinant antigen relative to the pre-treatment value for each individual, at the indicated time point (A), or with the 24 month follow up data stratified by microfilaremia status (B). In panel B, open circles indicate persistent Mf, closed circles indicate cleared Mf. Median values are indicated by the black bar. Significance as assessed by the Mann-Whitney U test is indicated (**** is p<0.0001, *** is p<0.001, ** p<0.01, ns is not significant).