Table 1.
Participant characteristics at breast tissue donation, overall and by PM2.5 component cluster, Komen Tissue Bank, 2009–2019
| Overall (n = 3,977) |
Cluster 1 (n = 2,866) |
Cluster 2 (n = 735) |
Cluster 3 (n = 376) |
|
|---|---|---|---|---|
| Census region, n (%) | ||||
| Midwest | 3327 (83.7%) | 2865 (100.0%) | 461 (62.7%) | 1 (0.3%) |
| Northeast | 111 (2.8%) | 1 (0.0%) | 29 (3.9%) | 81 (21.5%) |
| South | 260 (6.5%) | 0 (0%) | 245 (33.3%) | 15 (4.0%) |
| West | 279 (7.0%) | 0 (0%) | 0 (0%) | 279 (74.2%) |
| PM2.5 (ug/m3) | ||||
| Median [IQR] | 11.5 [5.6, 14.5] | 11.5 [6.8, 14.5] | 11.0 [5.6, 14.1] | 9.71 [6.1, 12.5] |
| Age at donation | ||||
| Mean (SD) | 43.8 (14.2) | 43.4 (14.0) | 44.4 (14.7) | 45.5 (14.5) |
| Race/ethnicity, n (%) | ||||
| Non-Hispanic Black | 728 (18.3%) | 622 (21.7%) | 77 (10.5%) | 29 (7.7%) |
| Non-Hispanic white | 2718 (68.3%) | 1996 (69.6%) | 557 (75.8%) | 165 (43.9%) |
| Hispanic | 336 (8.4%) | 174 (6.1%) | 74 (10.1%) | 88 (23.4%) |
| Other | 195 (4.9%) | 74 (2.6%) | 27 (3.7%) | 94 (25.0%) |
| Education, n (%) | ||||
| High school or less | 658 (16.5%) | 470 (16.4%) | 147 (20.0%) | 41 (10.9%) |
| Some college | 1001 (25.2%) | 680 (23.7%) | 218 (29.7%) | 103 (27.4%) |
| Bachelors | 1306 (32.8%) | 982 (34.3%) | 203 (27.6%) | 121 (32.2%) |
| Graduate degree or higher | 1012 (25.4%) | 734 (25.6%) | 167 (22.7%) | 111 (29.5%) |
| Mean (SD) | 29.7 (7.7) | 29.8 (7.8) | 30.0 (7.6) | 28.7 (7.2) |
| < 18.5 | 44 (1.1%) | 26 (0.9%) | 10 (1.4%) | 8 (2.1%) |
| 18.5 to < 25.0 | 1208 (30.4%) | 874 (30.5%) | 198 (26.9%) | 136 (36.2%) |
| 25.0 to < 30 | 1069 (26.9%) | 792 (27.6%) | 193 (26.3%) | 84 (22.3%) |
| ≥ 30 | 1656 (41.6%) | 1174 (41.0%) | 334 (45.4%) | 148 (39.4%) |
| Smoking status, n (%) | ||||
| Never | 2930 (73.7%) | 2106 (73.5%) | 542 (73.7%) | 282 (75.0%) |
| Former | 817 (20.5%) | 595 (20.8%) | 144 (19.6%) | 78 (20.7%) |
| Current | 230 (5.8%) | 165 (5.8%) | 49 (6.7%) | 16 (4.3%) |
| Menopause status, n (%) | ||||
| Premenopausal | 2610 (65.6%) | 1936 (67.6%) | 438 (59.6%) | 236 (62.8%) |
| Postmenopausal | 1367 (34.4%) | 930 (32.4%) | 297 (40.4%) | 140 (37.2%) |
| Urbanicity, n (%) | ||||
| Urban | 3574 (89.9%) | 2651 (92.5%) | 550 (74.8%) | 373 (99.2%) |
| Suburban | 387 (9.7%) | 204 (7.1%) | 181 (24.6%) | 2 (0.5%) |
| Rural | 16 (0.4%) | 11 (0.4%) | 4 (0.5%) | 1 (0.3%) |
| Percent fat on the slide, n (%) | ||||
| 0 to ≤25% | 250 (6.3%) | 190 (6.6%) | 30 (4.1%) | 30 (8.0%) |
| > 25 to ≤50% | 502 (12.6%) | 393 (13.7%) | 67 (9.1%) | 42 (11.2%) |
| > 50 to ≤75% | 887 (22.3%) | 679 (23.7%) | 136 (18.5%) | 72 (19.1%) |
| > 75–100% | 2338 (58.8%) | 1604 (56.0%) | 502 (68.3%) | 232 (61.7%) |
| Year of donation, n (%) | ||||
| 2009 | 353 (8.9%) | 319 (11.1%) | 34 (4.6%) | 0 (0%) |
| 2010 | 360 (9.1%) | 329 (11.5%) | 31 (4.2%) | 0 (0%) |
| 2011 | 483 (12.1%) | 321 (11.2%) | 159 (21.6%) | 3 (0.8%) |
| 2012 | 997 (25.1%) | 837 (29.2%) | 156 (21.2%) | 4 (1.1%) |
| 2013 | 387 (9.7%) | 193 (6.7%) | 12 (1.6%) | 182 (48.4%) |
| 2014 | 406 (10.2%) | 385 (13.4%) | 21 (2.9%) | 0 (0%) |
| 2015 | 231 (5.8%) | 76 (2.7%) | 136 (18.5%) | 19 (5.1%) |
| 2016 | 400 (10.1%) | 251 (8.8%) | 148 (20.1%) | 1 (0.3%) |
| 2017 | 193 (4.9%) | 84 (2.9%) | 27 (3.7%) | 82 (21.8%) |
| 2018 | 128 (3.2%) | 38 (1.3%) | 5 (0.7%) | 85 (22.6%) |
| 2019 | 39 (1.0%) | 33 (1.2%) | 6 (0.8%) | 0 (0%) |