Table 2.
Standardized beta regression coefficients from regression models with personality traits predicting glial fibrillary acidic protein (GFAP).
| Model 1 | Model 2 | |||||||
|---|---|---|---|---|---|---|---|---|
| Trait | β | L95%CI | U95%CI | p | β | L95%CI | U95%CI | p |
| Neuroticism | 0.083 | 0.023 | 0.142 | 0.007 | 0.079 | 0.018 | 0.140 | 0.012 |
| Extraversion | −0.103 | −0.162 | −0.043 | 0.001 | −0.085 | −0.147 | −0.024 | 0.007 |
| Openness | −0.051 | −0.111 | 0.009 | 0.097 | −0.047 | −0.111 | 0.016 | 0.146 |
| Agreeableness | 0.045 | −0.017 | 0.107 | 0.151 | 0.041 | −0.022 | 0.106 | 0.199 |
| Conscientiousness | −0.108 | −0.167 | −0.049 | <0.001 | −0.098 | −0.160 | −0.038 | 0.002 |
| N1: Anxiety | 0.098 | 0.038 | 0.158 | 0.001 | 0.093 | 0.031 | 0.154 | 0.003 |
| N2: Angry Hostility | 0.004 | −0.055 | 0.064 | 0.883 | 0.007 | −0.054 | 0.069 | 0.811 |
| N3: Depression | 0.077 | 0.018 | 0.137 | 0.010 | 0.075 | 0.014 | 0.137 | 0.016 |
| N4: Self-consciousness | 0.056 | −0.003 | 0.116 | 0.063 | 0.039 | −0.022 | 0.100 | 0.208 |
| N5: Impulsiveness | 0.016 | −0.043 | 0.076 | 0.590 | 0.039 | −0.023 | 0.101 | 0.222 |
| N6: Vulnerability | 0.120 | 0.061 | 0.178 | <0.001 | 0.103 | 0.042 | 0.164 | 0.001 |
| E1: Warmth | −0.007 | −0.067 | 0.053 | 0.825 | 0.012 | −0.049 | 0.074 | 0.693 |
| E2: Gregariousness | −0.022 | −0.081 | 0.038 | 0.475 | −0.012 | −0.072 | 0.048 | 0.692 |
| E3: Assertiveness | −0.110 | −0.168 | −0.051 | <0.001 | −0.088 | −0.149 | −0.026 | 0.005 |
| E4: Activity | −0.109 | −0.168 | −0.049 | <0.001 | −0.118 | −0.183 | −0.057 | <0.001 |
| E5: Excitement-Seeking | −0.056 | −0.118 | 0.006 | 0.079 | −0.043 | −0.108 | 0.021 | 0.183 |
| E6: Positive Emotions | −0.122 | −0.182 | −0.063 | <0.001 | −0.110 | −0.172 | −0.048 | 0.001 |
| O1: Fantasy | −0.043 | −0.103 | 0.017 | 0.163 | −0.039 | −0.102 | 0.024 | 0.221 |
| O2: Aesthetics | −0.029 | −0.089 | 0.031 | 0.349 | −0.025 | −0.087 | 0.037 | 0.427 |
| O3: Feelings | −0.109 | −0.169 | −0.049 | <0.001 | −0.102 | −0.164 | −0.040 | 0.001 |
| O4: Actions | −0.028 | −0.088 | 0.032 | 0.363 | −0.028 | −0.090 | 0.033 | 0.364 |
| O5: Ideas | −0.043 | −0.104 | 0.017 | 0.160 | −0.040 | −0.104 | 0.023 | 0.212 |
| O6: Values | 0.040 | −0.020 | 0.100 | 0.188 | 0.047 | −0.016 | 0.111 | 0.141 |
| A1: Trust | −0.025 | −0.085 | 0.036 | 0.418 | −0.022 | −0.085 | 0.040 | 0.481 |
| A2: Straightforwardness | 0.062 | 0.001 | 0.123 | 0.048 | 0.048 | −0.014 | 0.111 | 0.129 |
| A3: Altruism | 0.004 | −0.056 | 0.065 | 0.887 | 0.015 | −0.047 | 0.077 | 0.632 |
| A4: Compliance | 0.091 | 0.031 | 0.152 | 0.003 | 0.082 | 0.020 | 0.146 | 0.010 |
| A5: Modesty | 0.035 | −0.025 | 0.096 | 0.252 | 0.024 | −0.039 | 0.088 | 0.446 |
| A6: Tender-mindedness | 0.000 | −0.060 | 0.060 | 0.990 | 0.009 | −0.053 | 0.072 | 0.767 |
| C1: Competence | −0.099 | −0.158 | −0.040 | 0.001 | −0.076 | −0.137 | −0.015 | 0.014 |
| C2: Order | −0.093 | −0.151 | −0.034 | 0.002 | −0.091 | −0.150 | −0.031 | 0.003 |
| C3: Dutifulness | −0.079 | −0.138 | −0.020 | 0.008 | −0.078 | −0.139 | −0.017 | 0.012 |
| C4: Achievement Striving | −0.092 | −0.151 | −0.032 | 0.003 | −0.086 | −0.149 | −0.025 | 0.006 |
| C5: Self-Discipline | −0.102 | −0.160 | −0.043 | 0.001 | −0.097 | −0.159 | −0.037 | 0.002 |
| C6: Deliberation | −0.018 | −0.077 | 0.041 | 0.556 | −0.008 | −0.069 | 0.053 | 0.795 |
Notes: Model 1 N = 786; Model 2 N = 761. Model 1 include age and sex as covariates. Model 2 further include the time gap between personality assessment and the blood collection, eGFR, years of education, race (other vs. white), smoking, physical activity, body mass index, and disease burden. L95%CI and U95%CI are the lower and upper bound of the 95% Confidence interval. p < .05 and related β are bolded.