Table 3.

Standardized beta regression coefficients from regression models with personality traits predicting neurofilament light (NfL).

	Model 1				Model 2
Trait	β	L95%CI	U95%CI	p	β	L95%CI	U95%CI	p
Neuroticism	0.077	0.019	0.134	0.009	0.060	0.003	0.117	0.040
Extraversion	−0.096	−0.154	−0.039	0.001	−0.059	−0.117	−0.002	0.042
Openness	−0.057	−0.115	0.002	0.056	−0.040	−0.100	0.019	0.178
Agreeableness	0.003	−0.057	0.063	0.922	−0.013	−0.073	0.046	0.658
Conscientiousness	−0.046	−0.103	0.012	0.119	−0.026	−0.084	0.031	0.362
N1: Anxiety	0.069	0.011	0.127	0.020	0.052	−0.006	0.109	0.078
N2: Angry Hostility	0.033	−0.025	0.091	0.260	0.031	−0.026	0.088	0.285
N3: Depression	0.084	0.026	0.141	0.004	0.077	0.021	0.134	0.008
N4: Self-consciousness	0.076	0.019	0.133	0.009	0.047	−0.010	0.104	0.103
N5: Impulsiveness	−0.019	−0.077	0.039	0.516	−0.002	−0.060	0.056	0.941
N6: Vulnerability	0.099	0.042	0.156	0.001	0.060	0.003	0.117	0.039
E1: Warmth	−0.056	−0.114	0.002	0.056	−0.036	−0.094	0.021	0.210
E2: Gregariousness	−0.035	−0.093	0.022	0.227	−0.028	−0.084	0.028	0.328
E3: Assertiveness	−0.089	−0.146	−0.032	0.002	−0.037	−0.095	0.020	0.203
E4: Activity	−0.066	−0.124	−0.008	0.025	−0.056	−0.115	0.003	0.061
E5: Excitement-Seeking	−0.031	−0.091	0.030	0.322	−0.005	−0.065	0.055	0.874
E6: Positive Emotions	−0.122	−0.180	−0.065	<0.001	−0.087	−0.144	−0.029	0.003
O1: Fantasy	−0.028	−0.086	0.030	0.345	−0.015	−0.073	0.043	0.616
O2: Aesthetics	−0.081	−0.139	−0.023	0.006	−0.057	−0.114	0.000	0.050
O3: Feelings	−0.088	−0.147	−0.030	0.003	−0.078	−0.136	−0.020	0.009
O4: Actions	0.002	−0.056	0.060	0.953	0.020	−0.037	0.078	0.490
O5: Ideas	−0.064	−0.122	−0.006	0.032	−0.052	−0.111	0.007	0.086
O6: Values	0.044	−0.014	0.101	0.140	0.034	−0.025	0.093	0.259
A1: Trust	−0.030	−0.088	0.029	0.320	−0.042	−0.101	0.015	0.148
A2: Straightforwardness	0.043	−0.016	0.102	0.152	0.021	−0.038	0.080	0.481
A3: Altruism	−0.013	−0.071	0.045	0.662	−0.007	−0.065	0.050	0.797
A4: Compliance	0.012	−0.047	0.071	0.699	−0.017	−0.076	0.041	0.557
A5: Modesty	0.042	−0.016	0.101	0.153	0.026	−0.032	0.086	0.374
A6: Tender-mindedness	−0.057	−0.115	0.001	0.056	−0.038	−0.097	0.020	0.193
C1: Competence	−0.091	−0.148	−0.034	0.002	−0.061	−0.118	−0.005	0.034
C2: Order	−0.019	−0.076	0.039	0.526	−0.008	−0.065	0.048	0.768
C3: Dutifulness	−0.033	−0.090	0.024	0.254	−0.044	−0.101	0.013	0.127
C4: Achievement Striving	−0.021	−0.079	0.037	0.482	0.009	−0.049	0.067	0.760
C5: Self-Discipline	−0.037	−0.095	0.020	0.199	−0.020	−0.077	0.037	0.485
C6: Deliberation	−0.013	−0.071	0.044	0.645	−0.003	−0.060	0.053	0.910

Notes: Model 1 N = 786; Model 2 N = 761. Model 1 include age and sex. Model 2 further include the time gap between personality assessment and the blood collection, eGFR, years of education, race (other vs. white), smoking, physical activity, body mass index, and disease burden. L95%CI and U95%CI are the lower and upper bound of the 95% Confidence interval. p < .05 and related β are bolded.