Table 5.
Drug Liking bipolar VAS Emax—Ketamine Study.
| Ketamine Study | ||||||
|---|---|---|---|---|---|---|
| Statistic | Esmethadone 25 mg (N = 51) | Esmethadone 75 mg (N = 51) | Esmethadone 150 mg (N = 51) | Ketamine 0.5 mg/kg (N = 51) | DXM 300 mg (N = 51) | Placebo (N = 51) |
| Mean (SD) | 51.4 (3.28) | 54.9 (9.58) | 59.2 (14.38) | 90.0 (14.52) | 68.4 (18.39) | 50.9 (2.23) |
| Median | 50.0 | 50.0 | 51.0 | 100.0 | 60.0 | 50.0 |
| Range | 50–66 | 50–100 | 50–100 | 50–100 | 50–100 | 50–63 |
Drug Liking VAS is a bipolar scale where a score of 0 represents “strong disliking,” a score of 100 represents “strong liking,” and a score of 50 represents “neither like nor dislike” (neutral point). The question text is, “At this moment, my liking for this drug is?”.
Emax maximum effect, range minimum–maximum, SD standard deviation, VAS visual analog scale. Esmethadone and DXM were oral administration; ketamine IV administration.