Table 2.
Activation of mouse Tas2rs by bile acids.
| Max c (in µM) | Tas2r105 | Tas2r108 | Tas2r117 | Tas2r123 | Tas2r126 | Tas2r144 | |
|---|---|---|---|---|---|---|---|
| Cholic Acid | 1000 | 300 | 100 | 10 | 10 | 100 | 100 |
| Chenodeoxycholic Acid | 30 | ||||||
| Lithocholic Acid | 3 | 3 | |||||
| Deoxycholic Acid | 30 | 10 | 10 | 10 | |||
| Taurocholic Acid | 1000 | 100 | 30 | 100 | 300 | ||
| Glycocholic Acid | 1000 | 300 | 100 | 3 | 30 | 100 | 100 |
| Taurolithocholic Acid | 100 | 1 | 3 | ||||
| Ursodeoxycholic Acid | 30 | 10 |
Presentation of the mouse Tas2rs that were activated by bile acids. Determined threshold concentrations (p < 0.01) for receptor activation and maximum applied bile acid concentrations (Max c) are given in µM.