Fig. 2.

Protein expression (A) and G6Pase enzymatic activity (B) of hG6Pase-α variants directed by wild-type (WT) or hG6PC mRNA variants with additional targeted mutations at Ser-298. The experiments were performed as described under “Materials and methods” and legend for Fig. 1. Data were shown as percentage of wild-type (WT) group and presented as mean ± SEM of n = 3 samples from independent transfections. **p < 0.01; ****p < 0.0001 vs. WT