Fig. 1.

Delayed fracture healing in diabetic mice. (A) Images of two-month-old control and diabetic mice. (B) Radiographs of the samples from control and diabetic mice at different days after surgery. (C) Micro-CT 3D images of the whole femur after fracture. (D) Quantitative statistics of callus formation at different time points post-fracture was conducted. n = 5. (E–F) A quantitative statistical analysis of the micro-CT results of the healing tissues was performed. n = 5. (G–H) SOFG staining and quantitative statistics of callus sections. Scale bar in all images: 2.5 mm. n = 5. *P < 0.05; **P < 0.01; ***P < 0.001.