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. 2023 May 25;14:1151977. doi: 10.3389/fimmu.2023.1151977

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Copyright © 2023 Gao, Yu, Yan, Zhao and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Model fitted time-course plots of response rate for (A) PASI75, (B) PASI90 and (C) PASI100 for representative trials. Color symbols and vertical bars are observed mean and calculated weight of time points; gray symbols and lines are the model predictions. PASI, Psoriasis Area and Severity Index score; PASI75, PASI90 and PASI100, the proportion of patients achieving ≥75%, 90% and 100% respectively reduction from baseline PASI; s.c., subcutaneous injection; w, week; biw, twice weekly; q2w, once every 2 weeks; q4w, once every 4 weeks.