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Ranking of the treatments by predicting placebo-corrected median percent of patients with (A) PASI75, (B) PASI90, and (C) PASI100 at week 12 (descending order). Point estimates and 95% CIs were predicted from a model simulation of N = 10,000. Red dashed lines represent simulated placebo efficacy. PASI, Psoriasis Area and Severity Index score; PASI75, PASI90 and PASI100, the proportion of patients achieving ≥75%, 90% and 100% respectively reduction from baseline PASI; LD, loading dose.
