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. 2023 May 25;4:1149783. doi: 10.3389/fpain.2023.1149783

Table 2.

Summary of GUPI and SF-12 total and sub-scores at enrollment and at one-year follow-up.

IC/BPS OPPC p-value from t-test to compare IC/BPS and OPPC
Baseline Follow-up Change from baseline p-value1 Baseline Follow-up Change from baseline p-value1 Baseline Follow-up Change
GUPI, N 308 183 183 85 65 65
Mean (SD)2 Mean (SD)2 Mean (SD)3   Mean (SD)2 Mean (SD)2 Mean (SD)3        
Pain Symptom 12.5 (6.1) 14.0 (5.9) 1.1 (4.5) 0.002 16.6 (6.1) 18.1 (5.4) 1.2 (3.9) 0.022 <.001 <.001 0.806
Urinary Symptom 4.1 (2.9) 4.8 (2.9) 0.5 (2.4) 0.009 6.1 (2.9) 6.5 (2.5) 0.3 (2.3) 0.303 <.001 <.001 0.624
QoL sub-score 4.8 (3.3) 5.4 (3.2) 0.6 (2.4) <.001 7.0 (3.5) 7.7 (3.2) 0.6 (2.4) 0.039 <.001 <.001 0.952
Total 21.4 (10.9) 24.3 (10.5) 2.1 (7.5) <.001 29.8 (11.2) 32.4 (9.9) 2.1 (7.1) 0.018 <.001 <.001 0.993
SF-12, N 308 196 196 85 62 62    
Mean (SD)2 Mean (SD)2 Mean (SD)3 Mean (SD)2 Mean (SD)2 Mean (SD)3    
Physical Health 38.7 (11.0) 38.2 (9.5) −0.3 (8.8) 0.722 41.6 (12.0) 40.8 (11.4) −1.3 (7.3) 0.238 0.039 0.072 0.422
Mental Health 42.6 (12.8) 44.1 (11.9) 0.7 (10.5) 0.612 46.3 (11.4) 43.9 (12.2) 2.2 (8.3) 0.043 0.015 0.902 0.046
Total 81.3 (16.6) 82.3 (14.9) 0.4 (11.0) 0.413 87.9 (16.8) 84.7 (17.9) 3.5 (10.8) 0.027 0.001 0.294 0.015

Bolded items are statistically significant (p < 0.05).

BPS, Bladder pain syndrome; IC, Interstitial cystitis; GUPI, Genitourinary Pain Index; OPPC, Other pelvic pain conditions; SF-12, 12-item Short Form Health Survey.

1

Wilcoxon Signed-rank test to test the score change at one-year follow-up from baseline within each cohort.

2

A higher number means better health condition.

3

A positive number indicates health condition improved from baseline.