Table 1.

Presenting signs and symptoms of patients with PCH

Sign/symptom	Number (%) of patients∗
Dark urine/hemoglobinuria	88 (68.8)
Jaundice/scleral icterus	35 (27.3)
Fever	33 (25.8)
Weakness/fatigue/malaise	27 (21.3)
Pallor	22 (17.3)
Nausea/vomiting	17 (13.4)
Abdominal pain	17 (13.4)
Chills/rigors	10 (7.9)
Headache	3 (2.4)
Confusion/disorientation	3 (2.4)
Anorexia	3 (2.4)
Back/flank pain	3 (2.4)
Shortness of breath	3 (2.4)
Myalgia/arthralgia	2 (1.6)
Rash	2 (1.6)

^∗Among 128 patients in whom presenting signs/symptoms were reported; >1 symptom may have been reported in a single patient.