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. 2023 May 25;13:1167209. doi: 10.3389/fonc.2023.1167209

Table 2.

Diffusion parameters between the VETC-positive and VETC-negative groups and agreements between two radiologist.

Parameters Radiologist 1 Radiologist 2 ICC
VETC-negative VETC-positive P value VETC-negative VETC-positive P value
ADC (μm2/ms) 1.04 ± 0.21 1.01 ± 0.19 0.489 1.05 ± 0.20 1.05 ± 0.20 0.836 0.817
DKI_D (μm2/ms)* 1.48 ± 0.43 1.46 ± 0.34 0.986 1.50 ± 0.39 1.52 ± 0.33 0.795 0.784
DKI_K 0.55 ± 0.09 0.62 ± 0.09 0.001 0.55 ± 0.09 0.60 ± 0.09 0.008 0.948
SEM_DDC (μm2/ms) 1.64 ± 0.55 1.48 ± 0.51 0.164 1.66 ± 0.60 1.55 ± 0.48 0.367 0.859
SEM_α 0.55 ± 0.14 0.58 ± 0.13 0.248 0.54 ± 0.14 0.58 ± 0.12 0.188 0.964
FROC_D (μm2/ms) 1.00 ± 0.28 0.97 ± 0.22 0.486 1.02 ± 0.25 1.00 ± 0.22 0.794 0.727
FROC_β* 0.67 ± 0.12 0.66 ± 0.10 0.411 0.66 ± 0.13 0.65 ± 0.10 0.550 0.922
FROC_μ (μm) 3.47 ± 0.54 3.66 ± 0.41 0.068 3.50 ± 0.57 3.67 ± 0.31 0.075 0.929
CTRW_D (μm2/ms)* 1.31 ± 0.34 1.25 ± 0.27 0.494 1.32 ± 0.29 1.30 ± 0.29 0.616 0.793
CTRW_α 0.87 ± 0.07 0.91 ± 0.05 0.006 0.88 ± 0.07 0.91 ± 0.04 0.007 0.904
CTRW_β 0.66 ± 0.14 0.64 ± 0.13 0.615 0.64 ± 0.14 0.63 ± 0.12 0.786 0.917

Excepted where indicated, data are compared by using were compared using an independent sample t-test. *Date were compared by using a Mann-Whitney U test. ADC, apparent diffusion coefficient; DKI_D, diffusivity; DKI_K, kurtosis; SEM_DDC, distributed diffusion coefficient; SEM_α, intravoxel diffusion heterogeneity index; FROC_D, diffusion coefficient; FROC_β, fractional order derivative in space; FROC_μ, spatial constant; CTRW_D, anomalous diffusion coefficient; CTRW_α, temporal diffusion heterogeneity index; CTRW_β, spatial diffusion heterogeneity index; ICC, intraclass correlation coefficient.