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. 2023 May 25;17:1172805. doi: 10.3389/fnins.2023.1172805

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Copyright © 2023 Palmieri, Pozzer and Landsberger.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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State of the art of advanced RTT therapies. Summary of progresses made with various genetic approaches in in vitro and in vivo models of disease. Gene replacement therapy stands out as the only one so far that reached RTT girls.