Table 8.
Comparison of clinical indicators and serum Cat-S under grouping mode 2.
| Projects | Normal renal function group (n=141) | Decreased renal function group (n=59) | Z/χ2/t | P Value |
|---|---|---|---|---|
| Gender(female/male) a | 47/94 | 25/34 | 1.475 | 0.225 |
| Age (year) b | 55.29 ± 10.56 | 56.32 ± 10.21 | 0.636 | 0.526 |
| BMI (Kg/m2) b | 25.94 ± 3.33 | 26.73 ± 3.92 | 1.447 | 0.149 |
| SBP (mmHg) b | 133.37 ± 15.75 | 149.32 ± 19.68 | 5.528 | < 0.001 |
| DBP (mmHg) b | 76.89 ± 10.71 | 81.12 ± 13.03 | 2.383 | 0.018 |
| FBG (mmol/L) c | 7.45 (5.98, 9.33) | 7.00 (5.28, 9.29) | -1.421 | 0.155 |
| HbAlC (mmol/L) c | 8.40 (7.25, 9.90) | 8.00 (7.35, 8.90) | -1.644 | 0.100 |
| SUA (μmol/L) c | 281.0 (228.5, 347.0) | 374.0 (323.0, 447.0) | -5.754 | < 0.001 |
| Scr (μmol/L) c | 57.0(46.0, 64.0) | 124.0 (85.0, 193.0) | -10.663 | < 0.001 |
| eGFR mL/min/(1.73 m2) c |
131.75 (110.42, 158.49) | 48.66 (28.88, 71.84) | -11.143 | < 0.001 |
| BUN (mmol/L) c | 5.65 (4.87, 6.71) | 9.57 (7.65, 13.58) | -8.388 | < 0.001 |
| UACR (mg/g) c | 26.30(9.85, 172.00) | 3896.70(1487.40, 6345.60) | -8.503 | < 0.001 |
| TC (mmol/L) c | 4.57 (3.72, 5.44) | 5.20 (4.32, 6.62) | -3.682 | < 0.001 |
| TG (mmol/L) c | 1.52 (1.18, 2.27) | 2.00 (1.46, 2.59) | -2.644 | 0.008 |
| HDL-C (mmol/L) c | 1.08 (0.96, 1.31) | 1.09 (0.91, 1.31) | -0.441 | 0.659 |
| LDL-C (mmol/L) c | 2.67 (2.02, 3.29) | 3.13 (2.49, 4.04) | -3.338 | 0.001 |
| Cat-S (pg/mL) c | 594.24(374.05, 787.46) | 1642.78(1107.57, 2192.67) | -7.889 | < 0.001 |
| CysC (mg/L) c | 0.87 (0.78, 0.96) | 1.78 (1.25, 2.37) | -9.740 | < 0.001 |
| RBP (mg/L) c | 39.0 (33.8, 47.0) | 58.8 (47.3, 71.3) | -7.823 | < 0.001 |
normal renal function group (eGFR≥90mL/min/1.73 m2); decreased renal function group (eGFR<; 90mL/min/1.73 m2); a χ2 test; b one-way analysis of variance; c rank sum test.