| 1 |
What factors or tests best predict a prolonged recovery from concussion (known as postconcussion syndrome), and how can this information be used to develop a tailored strategy to manage the symptoms and support recovery? |
| 2 |
After a concussion, what is the best timing and approach to return to cognitive activities in educational settings (eg, school or university) and work settings to give the best outcome? |
| 3 |
What is the effectiveness of early referral and treatment by a concussion specialist team (eg, with combined medical assessment, physical therapies, mental health support, and other rehabilitation services) on concussion outcomes and length of recovery? |
| 4 |
After a concussion, what is the best approach for a return to physical activity, exercise, and sports (ie, timing, type, and intensity of activity) to give the best outcome? |
| 5 |
What is the most effective way to manage headache associated with concussion, and should people with a prior diagnosis of migraine be treated differently to get the best outcomes? |
| 6 |
What is the most effective way of differentiating prolonged concussion symptoms (known as postconcussion syndrome) from symptoms that are similar but unrelated to the concussion? |
| 7 |
What structural and/or functional (eg, molecular, biochemical) changes occur in the brain with a concussion? How do the intensity and direction of forces involved in the head trauma cause the brain injury, and does location of the brain injury impact symptoms and severity? |
| 8 |
What are the long-term effects of single or multiple concussions, and how do these effects impact day-to-day life? |
| 9 |
What is the correlation between concussion severity and disturbed sleep patterns? What tools, aids, medications, or other interventions are most effective in managing these sleep disturbances? |
| 10 |
How can the training of front-line physicians and other health care providers to recognize, diagnose, and manage concussion be improved and kept up to date? |
