Table 2.
Prophylactic Total Gastrectomy Decision Making Survey Results
| PTGneg (N=44) |
PTGpos (N=76) |
||
|---|---|---|---|
| Age at CDH1 diagnosis, median (range) | 54 (17-72) | 45 (20-66) | P=0.089 |
| Time to decision, median months (range) | 27 (8-71) | 8 (1-60) | P<0.001 |
| <12 months, N (%) | 7 (15.9) | 46 (60.5) | P<0.001 |
| ≥12 months, N (%) | 37 (84.1) | 30 (39.5) | |
| Decision for TG | |||
| Family history, N (%) | 16 (36.4) | 54 (71.1) | P<0.001 |
| EGD results, N (%) | 13 (29.5) | 13 (17.1) | P=0.111 |
| Doctor’s Recommendation, N (%) | 0 (0.0) | 13 (17.1) | n/a |
| More information, N (%) | 9 (20.5) | 0 (0.0) | n/a |
| Other, N (%) | 0 (0.0) | 0 (0.0) | n/a |
| Concerns/Values Included | P=0.021 | ||
| Yes, N (%) | 41 (93.2) | 76 (100.0) | |
| No, N (%) | 3 (6.8) | 0 (0.0) | |
| Relative s/p PTG, N (%) | 33 (75.0) | 59 (77.6) | P=0.743 |
| Family Death to GC | |||
| No, N (%) | 21 (47.7) | 13 (17.1) | P<0.001 |
| Yes, N (%) | 23 (52.3) | 63 (82.9) | |
| 1st or 2nd degree relative, N (%) | 19 (43.2) | 51 (67.1) | P=0.010 |
| Multiple Relatives, N (%) | 11 (25.0) | 22 (28.9) | P=0.641 |
PTG, prophylactic total gastrectomy; GC, gastric cancer.