Table 3.
Effect of nanoparticle shape and surface charge on macrophage polarization for tissue engineering.
| Type of nanoparticle | Size (nm) | Surface charge | Macrophage polarization | References |
|---|---|---|---|---|
| Silica NPs | 10–1000 | Negative | M1-type | [108] |
| Gold NPs | 10–300 | Negative | M1-type | [108] |
| Iron oxide NPs | 30–280 | Negative | M1-type | [108] |
| Polyurethane NPs | 35–60 | Negative | M1-type | [109] |
| NH2-polystyrene NPs | 200 | Positive | M2-type | [110] |
| PDA-modified Fe3O4 MNPs | 107 | Positive | M2-type | [111] |
| Hyaluronic acid-modified PEI-pDNA NPs | 120 | Positive | M2-type | [112] |
| Paramagnetic Fe3O4 MNPs | 15–30 | Positive | M2-type | [113] |
| Folate-modified Ag NPs | 28 | Positive | M2-type | [114] |
| Berbarin-loaded bilirubin-IgG NPs | 15 | Positive | M2-type | [115] |
| Poly-(lactic-co-glycolic) acid-Dox (PLGA-Dox) NPs | 76 | Negative | M1-type | [116] |
| Silymarin-PLGA NPs | 180 | Negative | M2-type | [117] |
| Fe3O4@C/MnO2 yolk-shell NPs | 160 | Negative | M2-type | [118] |
| Citrate-capped AuNPs | 13–22 | Negative | M2-type | [119] |
| Dox-loaded shMF NPs | 150–160 | Negative | M1-type | [120] |