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. 2023 May 10;64(6):100386. doi: 10.1016/j.jlr.2023.100386

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© 2023 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 2 — Adipocyte-specific ATGL KO mice have enhanced FABP4 secretion in vivo. Quantification of (A) plasma FABP4, (B) blood glucose, (C) body weight, and (D) plasma insulin in ATGL^fl/fl (black bars) and ATGL^AdpKO (red bars) mice under ad libitum-fed conditions, following 24 h food withdrawal, and 3.5 h after food was added back to cages (N = 15–17/group; two-way ANOVA). E: Plasma FABP4 in ATGL^fl/fl and ATGL^AdpKO following induction of lipolysis with ISO (10 mg/kg) (N = 15–16/group; two-way ANOVA). F: Plasma FABP4 levels in ATGL^fl/fl and ATGL^AdpKO mice injected with 10 μg recombinant FABP4 (N = 3–5/group; two-way ANOVA). G: Plasma insulin in ATGL^fl/fl and ATGL^AdpKO following induction of lipolysis with ISO (10 mg/kg) (N = 15–16/group; two-way ANOVA). All mouse experiments performed in 8- to 10-week-old male mice. Data are presented as mean ± SEM.