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. 2023 May 25;10:1061618. doi: 10.3389/fcvm.2023.1061618

Table 2.

Principal factors associated with the risk of recurrence of intracranial hemorrhage (ICH).

Factor Lower risk of recurrence Higher risk of recurrence
Type of ICH Subdural ICH, Epidural ICH Subarachnoid ICH, Lobar ICH
Cause of ICH Traumatic Spontaneous
Size of ICH Mild (i.e. volume)< 30 ml Moderate to severe
Presence of cerebral microbleedings No Yes
Amyloid angiopathy No Yes

ICH: intracranial hemorrhage.

Etiology, location, and imaging features of ICH are important factors in predicting the risk of recurrence Spontaneous bleedings are more likely to recur than traumatic ones, especially if cerebral microbleeds are shown by imaging. Indeed, in patients with a traumatic ICH, the restarting of OACs is likely to be related to a lower incidence of ischemic stroke and mortality rate (83). Notably, in these subjects, a higher recurrence of ICH has also not been reported (83). On the contrary, a relationship between anticoagulation strategy and recurrent ICH has been described in patients with AF after a non-traumatic ICH. Remarkably, the cerebral microbleeds (CMBs) neuroimaging finding is likely to be more strictly associated with a greater recurrence of ICH (84).