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. 2023 May 24;8(22):20056–20065. doi: 10.1021/acsomega.3c02331

Table 1. IC50 and SI Data for Compounds 2, 3a–j, and Cisplatin.

compound IC50 (μM)
SIa
A549 cell line L929 cell line
2 >500 >500  
3a 91.35 ± 21.89 >500 >5.47
3b 410.15 ± 220.38 >500  
3c >500 >500  
3d >500 >500  
3e 176.23 ± 56.50 >500 >2.84
3f 250.61 ± 45.87 >500  
3g 46.60 ± 6.15 276.67 ± 28.87 5.94
3h >500 >500  
3i 83.59 ± 7.30 >500 >5.98
3j >500 >500  
Cisplatin 23.89 ± 2.71    
a

SI = IC50 for L929 cells/IC50 for A549 cells.