Table 4. Biodistribution of 131I-4b in Normal Micea.
injected dose/gram tissue at different time intervals, % |
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---|---|---|---|---|
organs and body fluids | 1/2 h | 1 h | 2 h | 4 h |
blood | 7.1 ± 0.5b | 6.9 ± 0.3b | 4.4 ± 0.3b | 1.8 ± 0.3b |
bone | 1.1 ± 0.03b | 1.2 ± 0.02b | 0.8 ± 0.7b | 0.8 ± 0.02b |
liver | 5.4 ± 0.5b | 6.9 ± 0.4b | 8.4 ± 0.7 | 2.7 ± 0.02 |
stomach | 12.3 ± 1.2 | 16.0 ± 1.6b | 14.1 ± 1.2b | 10.2 ± 0.9b |
intestine | 5.1 ± 0.3b | 4.4 ± 0.3b | 3.1 ± 0.3b | 2.9 ± 0.2b |
lung | 3.9 ± 0.3b | 6.4 ± 0.6b | 4.6 ± 0.5b | 3.2 ± 0.2b |
heart | 5.2 ± 0.3b | 5.0 ± 0.4b | 3.6 ± 0.3b | 1.7 ± 0.01b |
spleen | 3.1 ± 0.2b | 2.7 ± 0.2 | 2.3 ± 0.2b | 1.1 ± 0.02 |
kidney | 3.9 ± 0.4b | 6.2 ± 0.5b | 5.8 ± 0.6b | 4.5 ± 0.3b |
urine | 5.1 ± 0.6b | 7.5 ± 0.5b | 14.3 ± 1.2b | 18.1 ± 1.3b |
brain | 0.4 ± 0.06b | 0.5 ± 0.03b | 0.6 ± 0.06b | 0.7 ± 0.03b |
thyroid | 2.7 ± 0.2b | 4.8 ± 0.4 | 7.6 ± 0.6b | 9.4 ± 1.2 |
normal muscle | 1.4 ±0.07b | 1.6 ± 0.08 | 1.5 ± 0.05b | 1.9 ± 0.08 |
Values expressed as mean ± SEM, n = 3.
Significantly different from each previous value of each organ using unpaired Student’s t-test (P ≤ 0.05).