Table 5. Biodistribution of ¹³¹I-4b in Solid Tumor-Bearing Mice^a.

	injected dose/gram tissue at different time intervals, %
organs and body fluids	1/2 h	1 h	2 h	4 h
blood	7.1 ± 0.5c	6.1 ± 0.4c	4.0 ± 0.3c	1.5 ± 0.03c
bone	1.1 ± 0.03c	0.9 ± 0.02c	0.6 ± 0.01c	0.8 ± 0.02c
liver	5.5 ± 0.5c	6.2 ± 0.4c	8.0 ± 0.7	2.1 ± 0.2
stomach	13.3 ± 1.4	15.0 ± 1.3c	14.1 ± 1.2c	10.2 ± 1.1c
intestine	5.5 ± 0.3c	4.5 ± 0.2c	3.3 ± 0.3c	2.8 ± 0.2c
lung	3.8 ± 0.3c	11.6 ± 1.1c	6.3 ± 0.5c	3.1 ± 0.2c
heart	5.6 ± 0.3c	4.0 ± 0.3c	3.6 ± 0.3c	1.5 ± 0.01c
spleen	3.3 ± 0.1c	2.5 ± 0.02	2.3 ± 0.05c	1.1 ± 0.02
kidney	3.6 ± 0.3c	4.6 ± 0.3c	6.6 ± 0.6c	2.5 ± 0.3c
urine	3.4 ± 0.4c	7.5 ± 0.5c	11.3 ± 1.1c	14.1 ± 1.2c
brain	0.3 ± 0.02c	0.4 ± 0.03c	0.6 ± 0.06c	0.7 ± 0.03c
thyroid	3.7 ± 0.5c	5.8 ± 0.5	7.6 ± 0.6c	9.4 ± 0.8
normal muscle	1.1 ± 0.04c	1.2 ± 0.05	1.4 ± 0.09c	1.3 ± 0.07
tumor muscle	3.6 ± 0.3c	7.5 ± 0.6	10.0 ± 1.1c	3.1 ± 0.2
T/NT ratiob	3.2 ± 0.2c	6.2 ± 0.5	7.1 ± 0.6c	2.4 ± 0.2
T/blood ratio	0.5 ± 0.03c	1.2 ± 0.02	2.5 ± 0.3c	2.1 ± 0.2

^aValues expressed as mean ± SEM, n = 3.

^bT/NT: tumored (muscle)/nontumored (muscle).

^cSignificantly different from each previous value of each organ using unpaired Student’s t-test (P ≤ 0.05).