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. 2023 May 19;8(22):19145–19167. doi: 10.1021/acsomega.2c08016

Table 1. Topical Drug Delivery Intended for Several Skin Diseases.

Disease Therapeutic agent Animal model Route Reference
Acne Adapalene Rabbit auricle Topical (74)
Acne vulgaris Retinyl palmitate Female Wistar rats Topical (75)
Acne Azelaic acid, tea tree oil Female Wistar rats, testosterone-induced skin acne male Swiss albino mice Topical (76)
Acne Dapsone Male BALB/c mouse Topical (77)
Acne Isotretinoin, clindamycin phosphate Testosterone-induced skin acne male laca mice Topical (78)
Skin fungal infections Ketoconazole Albino rabbits, Wistar rats Topical (79)
Skin infections and disorders Rhein Male Wistar rats Topical (80)
Skin infection Garvicin KS, micrococcin P1 BALB/cJRj mice Topical (81)
Skin fungal infections Miconazole Albino rats Topical (82)
Skin fungal infections Luliconazole Candida albicans induced skin fungal infection Albino rats Topical (83)
Psoriasis Gemcitabine HCL, tacrolimus, methotrexate sodium, triamcinolone, betamethasone 17-valerate 12-O-Tetradecanoylphorbol 13-acetate-induced skin hyperplasia and inflammation male Swiss mice Topical (84)
Face skin cancer Small interfering RAN Mouse xenograft model Topical (85)
Inflammatory skin disorders Pioglitazone Arachidonic-induced inflammatory skin BALB/c male mice Topical (86)
Psoriatic skin lesions Imiquimod, curcumin Psoriasis-induced mice, skin of male Albino rats Topical (87)
Cutaneous leishmaniasis Amphotericin B Female BALB/c mice Topical (88)