Table 3.

Cox proportional hazards*

Variable	Univariable analyses		Multivariable analyses
	Hazard ratio (95% confidence interval)	p value	Hazard ratio (95% confidence interval)	p value
Age at perforation (referent: incremental increasing age by year)	1.01 (0.99–1.03)	0.18	0.99 (0.99–1.03)	0.37
Gender (referent: male)	1.01 (0.62–1.62)	0.98	1.06 (0.64–1.76)	0.80
Corticosteroids (referent: no corticosteroids)	1.59 (0.94–2.67)	0.09	1.75 (1.02–2.99)	0.04
Time since last bevacizumab dose (referent: incremental time by weeks)	0.99 (0.99–.00)	0.82	1.00 (0.99–1.00)	0.37
Surgery (referent: no surgery)	0.49 (0.31–0.78)	0.003	0.47 (0.29–0.74)	0.002

^*Smaller hazard ratios are indicative of longer survival