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. 2023 Jun 8;13:103. doi: 10.1186/s13578-023-01061-z

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — A, E: Violin plot showing the NCS values of each cell subpopulation in LUAD (A) and ESCC (E) tumors and normal tissues beside the tumors; B, F: UMAP plot showing the high and low NCS values of each cell in LUAD (B) and ESCC (F) tumors and normal tissues beside the tumors; C, G: Separating LUAD (C) and ESCC (G) tumor cells into two groups of high and low NCS; D, H: Tumor and peri-tumor normal tissues were separated according to UMAP, and all cells of LUAD (C) and ESCC (G) were divided into two groups according to the average value of NCS