Table 3.
HDS Results of Infertility Cohort. Shows the High DNA Stainability (HDS) results of our cohort of 209 human male infertility subjects on the sperm chromatin structure analysis test performed on their semen samples. This HDS was analyzed as a continuous variable and as a binary (HDS over 10% or under or equal to 10%). This was done as a logistics regression model for the categorical variables and a linear regression model for the continuous variables. No significant relationships were found
Outcome: HDS > 10% or HDS ≤ 10% | |||||
Variable | Value | Estimate | Standard error | Wald Chi-Square | p-value |
Age | age in years | -0.05 | 0.03 | 2.59 | 0.1077 |
Exposure to heat (yes/no) | yes | -0.06 | 0.19 | 0.09 | 0.7591 |
Outside/inside job | inside | 4.09 | 1.82 | 0.00 | 0.9821 |
Outside/inside job | outside | 4.26 | 1.82 | 0.00 | 0.9813 |
Exposure to radiation/chemicals (yes/no) | yes | 0.04 | 0.20 | 0.05 | 0.8281 |
Tobacco use (yes/no) | yes | 0.25 | 0.18 | 1.89 | 0.1687 |
Level of alcohol use | heavy | -0.04 | 0.36 | 0.01 | 0.9121 |
Level of alcohol use | moderate | 0.29 | 0.25 | 1.31 | 0.2519 |
Level of alcohol use | rare | -0.27 | 0.25 | 1.10 | 0.2951 |
Outcome: HDS (%) continuous variable | |||||
Variable | Value | Estimate | Standard error | t-value | p-value |
Age | age in years | -0.10 | 0.08 | -1.29 | 0.1985 |
Exposure to heat (yes/no) | yes | 1.03 | 1.08 | 0.96 | 0.3406 |
Outside/inside job | inside | 4.08 | 4.20 | 0.97 | 0.3315 |
Outside/inside job | outside | 3.00 | 4.28 | 0.70 | 0.4845 |
Exposure to radiation/chemicals (yes/no) | yes | 1.13 | 1.11 | 1.02 | 0.3108 |
Tobacco use (yes/no) | yes | 1.83 | 1.01 | 1.81 | 0.0726 |
Level of alcohol use | heavy | -1.09 | 1.44 | -0.76 | 0.4500 |
Level of alcohol use | moderate | 0.77 | 1.10 | 0.70 | 0.4855 |
Level of alcohol use | rare | 0.01 | 1.07 | 0.01 | 0.9892 |
HDS High DNA Stainability