Table 1.
Patient ID | WHO 2016 | IPSS | Agerange | Sex | Karyotype | Tracking lesions |
---|---|---|---|---|---|---|
P01 | MDS-MLD | low | 60–65 | m | 46,XY[20] | TET2 |
P02 | MDS-EB1 | int-1 | 60–65 | m | 46,XY[20] | SF3B1 |
P03 | MDS-MLD | int-2 | 70–75 | m | 46,XY[20] | Not detected |
P04 | MDS-EB1 | int-2 | 60–65 | m | 46,XY, + 1.der(1;16)(q10;p10)[18/20] | RUNX1, IDH1, IDH2, SRSF2 |
P05 | MDS-EB2 | high | 60–65 | m | 45,X, -Y [11]; 45,X,-Y,del(9)(q21q32) [5]; 45,X,-Y,del(9)(q13q34)[4] | KRAS |
P06 | MDS-EB2 | int-2 | 40–45 | f | 45,XX,-7[15] | IDH2 |
P07 | MDS-MLD | int-1 | 70–75 | m | 46,XY[20] | Not detected |
P08 | MDS-RS-MLD | low | 70–75 | m | 46,XY[20] | SF3B1 |
P09 | MDS-MLD | int-1 | 80–85 | m | 46,XY[20] | Not detected |
P10 | MDS-MLD | int-1 | 80–85 | f | 46, XX[25] | ASXL1, DNMT3A |
P11 | MDS-EB1 | int-1 | 55–60 | f | 46,XX[20] | TP53, SF3B1 |
P04_2 | MDS-EB1 | int-2 | 60–65 | m | 46,XY, + 1.der(1;16)(q10;p10)[18/20] | RUNX1, IDH1, IDH2, SRSF2 |
The table displays the WHO classification 2016, IPSS, age, sex and karyotype of the MDS patients whose MSCs were used for experiments
MDS Myelodysplastic Neoplasms, IPSS MDS risk score according to international prognostic scoring system, int Intermediate, m Male, f Female