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. 2023 Jun 8;24:386. doi: 10.1186/s13063-023-07384-z

Table 3.

Relative risks for mean arterial pressure (MAP) and heart rate (HR) decrease > 20% of baseline compared with Group NS

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Group MD: midazolam 0.03 mg/kg for anaesthesia induction. Group NS: normal saline at the rate of 60 ml/h for 15 min before anaesthesia induction + 0.125 ml/kg/h continuous infusion until the end of operation. Group D0.25: dexmedetomidine 0.25 μg/kg for 15 min before anaesthesia induction + 0.5 μg/kg/h continuous infusion until the end of operation. Group D0.5: dexmedetomidine 0.5 μg/kg for 15 min before anaesthesia induction + 0.5 μg/kg/h continuous infusion until the end of operation. Group D0.75: dexmedetomidine 0.75 μg/kg for 15 min before anaesthesia induction + 0.5 μg/kg/h continuous infusion until the end of operation

*Statistically significant (P < 0.05)