Table 1.
Overall prevalence of meningitis after EIS and subgroup analysis by WHO region, continent, and income
| Variable | No. of studies (no. of patients) | Pooled prevalence (95% CI) | I2 (%) | P-value (Cochran’s Q) | 95% prediction interval |
|---|---|---|---|---|---|
| Overall | 83 (30,959) | 1.6 (1.1–2.1) | 88 | < 0.01 | 0.0–7.4 |
| WPR | 25 (6421) | 2.4 (1.1–4.2) | 92 | < 0.01 | 0.0–15.3 |
| AMR | 24 (10,462) | 0.9 (0.4–1.6) | 84 | < 0.01 | 0.0–4.9 |
| EUR | 27 (7730) | 1.4 (0.8–2.3) | 82 | < 0.01 | 0.0–6.8 |
| EMR | 3 (202) | 3.9 (0.2–10.7) | 68 | 0.04 | – |
| SEAR | 3 (5993) | 1.8 (1.2–2.6) | 24 | 0.27 | 0.0–12.7 |
| Asia | 31 (12,566) | 2.5 (1.4–3.7) | 90 | < 0.01 | 0.0–11.4 |
| Europe | 26 (7679) | 1.4 (0.7–2.2) | 82 | < 0.01 | 0.0–6.7 |
| North America | 22 (10,022) | 0.9 (0.3–1.5) | 85 | < 0.01 | 0.0–4.9 |
| South America | 2 (440) | 1.5 (0.0–4.7) | 73 | 0.05 | – |
| Africa | 2 (252) | 1.2 (0.1–3.1) | 0 | 0.90 | – |
| LMICs | 24 (9899) | 2.7 (1.6–4.1) | 88 | < 0.01 | 0.0–11.4 |
| HICs | 59 (21,060) | 1.2 (0.8–1.7) | 83 | < 0.01 | 0.0–5.6 |
WPR: Western Pacific Region; AMR: Americas Region; EUR: European Region; EMR: Eastern Mediterranean Region; SEAR: South-East Asian Region; LMIC: low- and middle-income countries; HIC: high-income countries