Table 2:

DNT NAMs bioactivity of seven selected PFAS

The total number of positive responses (hit sum) out of the total number of endpoints tested (N tested endpoints) is shown for multi-concentration (mc) or single-concentration (sc). PFAS were given a QC grade of either pass (P) or fail (F). QC flags include ‘Z’ (MW Confirmed, No Purity Info), ‘Fns’ (caution, no sample detected, biological activity unreliable), ‘Fde’ (caution, degradation of analyte evident, in some instances due to DMSO), ‘P’ (pseudo-parent monitored or adduct monitored; no direct confirmation that parent analyte is present), and ‘I’ (Isomers; two or more isomers detected).

PFAS	DTXSID	QC Pass/Fail	QC.flags	Mc hit sum	Mc N tested endpoints	SC hit sum	Sc N tested endpoints	Bioactivity
PFOA	DTXSID8031865	P	Z	1	19			Equivocal
GenX	DTXSID70880215	F	Fns, Fde, P	0	27			Inactive
PFOS	DTXSID3031864	P	Z, I	0	27			Inactive
PFHxA	DTXSID3031862	P	Z	0	19			Inactive
PFBS	DTXSID5030030	P	Z	0	19			Inactive
PFHpS	DTXSID8059920	P	Z			1	14	Equivocal
PFHxS	DTXSID7040150	P	Z, I			0	14	Inactive