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. Author manuscript; available in PMC: 2023 Jun 8.
Published in final edited form as: Neuromolecular Med. 2022 Nov 30;25(1):94–101. doi: 10.1007/s12017-022-08731-0

Fig. 3: GSK-3β inhibitor VIII prevented GSK-3β S9 dephosphorylation, leading to reduced tau phosphorylation after transient focal ischemia.

Fig. 3:

Treatment with GSK-3β Inhibitor VIII at 30 min of reperfusion following transient MCAO reversed post-ischemic changes in both GSK-3β phosphorylation and tau phosphorylation compared to vehicle control. GSK-3β Inhibitor VIII did not change the protein levels of total tau and total GSK-3β. Each band in the blot is the biological representation. Values are mean ± SD (n=4/group); *p<0.05 compared with vehicle control by Mann-Whitney U test.