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. Author manuscript; available in PMC: 2023 Jun 8.
Published in final edited form as: Nat Genet. 2022 Dec 12;55(1):112–122. doi: 10.1038/s41588-022-01248-z

Fig. 1 |. Scheme of data generation and analysis overview.

Fig. 1 |

Multi-tissue DNAm Illumina EPIC-array-based profiles are integrated with GTEx project sample-matched gene expression to map DNAm-expression correlations (eQTMs). Sample-matched genotype data are integrated to map mQTLs and eQTLs. e/mQTL signal is colocalized with GWAS data and multi-context eQTLs, and integrated with eQTMs and functional maps, to link variants and genes to traits. This figure was created with adapted templates from http://biorender.com.