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. Author manuscript; available in PMC: 2023 Sep 2.
Published in final edited form as: ACS Catal. 2022 Aug 15;12(17):10581–10586. doi: 10.1021/acscatal.2c03400

Table 4.

Site-selective Arylation of Pentan-2-one with Different TDGa, b

graphic file with name nihms-1897078-t0005.jpg
a

Conditions: 1 (0.1 mmol, 1.0 equiv), methyl 4-iodobenzoate (2.0 equiv), Pd(OAc)2 (10 mol%), TDG (30 mol%), L12 (60 mol%), AgTFA (3.0 equiv) and ClCH2COOH (1.0 equiv) in HFIP (0. 5 mL), 120°C, under air, 12 h.

b

Yield and ratio determined by 1H NMR of the crude mixture.

c

Reaction time: 48h.