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. 2023 May 25;11:1103393. doi: 10.3389/fpubh.2023.1103393

Table 3.

Subgroup analyses of the association between metabolic health-obesity (defined by %BF) phenotypes and kidney stones.

Subgroup MHN OR (95% CI) MHOW OR (95% CI) MHO OR (95% CI) MUN OR (95% CI) MUOW OR (95% CI) MUO OR (95% CI) P for interaction
Sex 0.395
Male Reference 0.45 (0.07–2.92) 1.35 (0.30–6.13) 0.54 (0.17–1.70) 1.19 (0.39–3.63) 1.63 (0.56–4.79)
Female Reference 3.18 (0.75–13.39) 4.87 (1.34–17.69) 5.16 (1.28–20.83) 5.29 (1.48–18.93) 6.35 (1.94–20.75)
Age 0.082
<40 years Reference 2.94 (0.79–10.86) 4.32 (1.23–15.13) 5.18 (1.41–18.94) 4.88 (1.59–14.97) 5.57 (1.78–17.44)
≥40 years Reference 0.18 (0.03–1.13) 1.50 (0.25–9.12) 0.27 (0.05–1.53) 0.86 (0.24–3.03) 1.28 (0.36–4.52)
Smoking status 0.947
Current smokers Reference 1.16 (0.06–23.13) 2.48 (0.31–19.64) 1.61 (0.21–12.52) 2.21 (0.32–15.46) 3.12 (0.46–21.11)
Non-current smokers Reference 1.57 (0.51–4.87) 3.02 (1.06–8.64) 2.22 (0.69–7.17) 2.90 (1.14–7.41) 3.51 (1.48–8.33)
Physical activity status 0.271
Active Reference 2.12 (0.10–11.22) 3.89 (0.95–15.88) 3.22 (0.71–14.60) 2.88 (0.74–11.22) 3.31 (0.87–12.52)
Inactive Reference 1.13 (0.31–4.20) 2.37 (0.72–7.86) 0.87 (0.24–3.21) 2.65 (0.92–7.64) 3.68 (1.29–10.50)

%BF, percent body fat; MHN, metabolically healthy normal weight; MHOW, metabolically healthy overweight; MHO, metabolically healthy obesity; MUN, metabolically unhealthy normal weight; MUOW, metabolically unhealthy overweight; MUO, metabolically unhealthy obesity; OR, odds ratio; CI, confidence interval. Multivariable model was adjusted for age (except for age subgroups), sex (except for sex subgroups), race and ethics, education level, smoking status (except for smoking status subgroups), alcohol consumption, physical activity (except for physical activity subgroups), daily water intake, CKD stage 3–5, and hyperuricemia.