Table 1:
Demographics of patients with negative and positive cytology.
| Negative cytology at PIPAC#1 n=31 patients | Positive cytology at PIPAC#1 n=44 patients | p-Value | |
|---|---|---|---|
| Demographics | |||
| Median age (IQR) | 63 (48–71) | 62 (54–69) | 0.99 |
| Gender male, n (%) | 11 (35 %) | 14 (32 %) | 0.71 |
| ASA III-IV, n (%) | 6 (19 %) | 16 (36 %) | 0.19 |
| ECOG 0-I, n (%) | 21 (68 %) | 35 (80 %) | 0.28 |
| Disease origin | 0.52 | ||
| Ovarian, n (%) | 13 (42 %) | 17 (39 %) | |
| Colorectal, n (%) | 9 (29 %) | 15 (34 %) | |
| Gastric, n (%) | 1 (3 %) | 1 (2 %) | |
| Hepatobiliary, n (%) | 2 (6 %) | 5 (11 %) | |
| Mesothelioma, n (%) | 6 (20 %) | 6 (14 %) | |
| Previous systemic chemotherapy | |||
| ≥3 lines in total | 11 (35 %) | 18 (41 %) | 0.63 |
| ≥12 cycles in total | 29 (93 %) | 35 (80 %) | 0.45 |
| Symptoms before PIPAC procedures | |||
| Abdominal pain, n (%) | 3 (10 %) | 10 (23 %) | 0.22 |
| Ascites, n (%) | 5 (16 %) | 17 (39 %) | 0.04 |
| Obstructive symptoms (ileus), n (%) | 4 (13 %) | 2 (5 %) | 0.22 |
| Ascites drainage within last 4 weeks before PIPAC, n (%) | 0 | 6 (14 %) |
Median (IQR, interquartile rang or range), mean (SD, standard deviation) or number (%) as appropriate. Statistical significance (p<0 05) is highlighted in bold. ASA, American Association of Anesthesiologists physical status classification system. ECOG Performance Status Scale.