Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 8;13:9361. doi: 10.1038/s41598-023-36567-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

scRNAseq analysis reveals distinct clusters of primary cultured CECs. (a) UMAP of the 42,220 sequenced cells reveals six cell clusters. (b) Gene expression UMAP of typical CEC markers namely ALCAM (CD166), PRDX6, PITX2, SLC4A11, and ATP1A1 confirms the endothelial identity of the sequenced cells. (c) Violin plots show gene expression for markers of endothelium (ALCAM, COL4A3), senescence (CDKN2A, TAGLN), proliferation (MKI67, CENPF), and fibrosis (CD44, ACTA2). (d) Bar charts show the distribution of cells of each donor per cluster (top) and the time point composition of each cluster (bottom).