Table 2.
Proportion of Participants With Prolonged Fatigue Symptoms at 3 Months by Variant of Concern Time Period in Severe Acute Respiratory Syndrome Coronavirus 2–Positive Participants
| Fatigue Symptoms | Variant of Concern Time Period | P Value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Overall (N = 2373)a | Pre-Delta (n = 456) | Delta (n = 1179) | Omicron (n = 738) | ||||||
| Fatigue, tiredness, or exhaustion | 838 | (35.3) | 161 | (35.3) | 407 | (34.5) | 270 | (36.6) | .655 |
| Muscle aches/muscle pains | 366 | (15.4) | 88 | (19.3) | 156 | (13.2) | 122 | (16.5) | .006 |
| Pain in joints | 312 | (13.2) | 66 | (14.5) | 141 | (12.0) | 105 | (14.2) | .233 |
| Unrefreshing sleep | 601 | (25.3) | 121 | (26.5) | 288 | (24.4) | 192 | (26.0) | .594 |
| Sleep disturbance | 652 | (27.5) | 129 | (28.3) | 304 | (25.8) | 219 | (29.7) | .163 |
| Forgetfulness/memory problems | 297 | (12.5) | 79 | (17.3) | 137 | (11.6) | 81 | (11.0) | .002 |
| Difficulty thinking or concentrating | 294 | (12.4) | 70 | (15.4) | 143 | (12.1) | 81 | (11.0) | .077 |
| Dizziness or fainting | 149 | (6.3) | 36 | (7.9) | 68 | (5.8) | 45 | (6.1) | .274 |
| Fatigue Severity Score ≥25 | 302 | (12.7) | 76 | (16.7) | 135 | (11.5) | 91 | (12.3) | .017 |
Data are presented as No. (%) unless otherwise indicated.
Twenty-nine patients were excluded due to missing data at 3 months.