Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Sequence elements in the PvuII–AvaII region silence splicing of the C-β intron in HeLa nuclear extracts. (A) A scheme of the PvuII–AvaII region, including the polyadenylation signal (pA) and cleavage site (scissors), is shown. Constructs A–F are depicted. (B) Splicing reactions of pre-mRNAs A–F (indicated above lanes). Incubations were for 2 h. Pre-mRNAs, lariat intermediates and mRNA products are labelled on the right; an asterisk also shows the mRNA products.
