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. 2023 May 25;13:1181522. doi: 10.3389/fonc.2023.1181522

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Copyright © 2023 Chen, Li and Yu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Kaplan–Meier plots of DFS contrasting high versus low expression of CA199, absence versus presence of LVI, high-Ki67 versus low-Ki67, and dMMR versus pMMR. (A) Association between DFS and serum CA199 expression: patients with high serum CA199 expression had significantly shorter DFS (p<0.001). (B) Association between DFS and LVI expression: patients with present LVI had significantly shorter DFS (p<0.001). (C) Association between DFS and Ki67 expression: patients in the high-Ki67 group had shorter DFS (p =0.01). (D) Association between DFS and MMR expression: patients with pMMR had significantly shorter DFS (p =0.031).