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. 2023 May 4;51(10):4995–5005. doi: 10.1093/nar/gkad317

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© The Author(s) 2023. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — Core defense hotspot 1 (cDHS1). (A) Representative isolates with cDHS1 chosen to show the diversity in anti-phage systems. Dark gray genes are marker genes that define the boundaries of the hotspot. Light gray genes indicate non-defense genes and are neighbors to the defense system which are colored based on the publication they were discovered in. (B) Pie chart of the different immune systems found in cDHS1, colored by publication. (C) Size distribution of cDHS1 in kb. (D) GC% difference between the host chromosome and the defense hotspot.